Fabio Di Domenico Selected Research

biliverdin reductase

4/2019	Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease.
1/2019	Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease.
1/2019	Reduced biliverdin reductase-A levels are associated with early alterations of insulin signaling in obesity.
10/2018	Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease.
2/2016	Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm.
2/2014	The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: it's time for reconciliation.
7/2013	Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain.
1/2012	Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease.
1/2012	HO-1/BVR-a system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: a potential biochemical marker for the prediction of the disease.
4/2011	Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.

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Fabio Di Domenico Research Topics

Disease

41	Alzheimer Disease (Alzheimer's Disease) 04/2021 - 02/2009
18	Cognitive Dysfunction 11/2021 - 02/2009
12	Insulin Resistance 11/2021 - 09/2014
10	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2011
6	Amyloid Plaque 10/2018 - 08/2013
5	Mitochondrial Diseases (Mitochondrial Disease) 11/2021 - 10/2014
5	Down Syndrome (Down's Syndrome) 01/2019 - 06/2014
4	Neoplasms (Cancer) 01/2020 - 12/2010
2	Carcinogenesis 01/2020 - 03/2010
2	Dementia (Dementias) 12/2018 - 02/2016
2	Parkinson Disease (Parkinson's Disease) 10/2017 - 12/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 05/2015 - 07/2013
2	Virus Diseases (Viral Diseases) 10/2013 - 01/2009
1	Atrophy 01/2021
1	Tauopathies 01/2021
1	Trisomy (Trisomies) 01/2021
1	Infections 06/2020
1	Herpes Simplex 06/2020
1	Rett Syndrome (Rett's Disorder) 06/2020
1	Nervous System Diseases (Neurological Disorders) 06/2020
1	Genomic Instability 01/2020
1	Skin Neoplasms (Skin Cancer) 01/2020
1	Fatty Liver 01/2019
1	Obesity 01/2019
1	Disease Progression 10/2018
1	Metabolic Diseases (Metabolic Disease) 10/2017
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2017
1	Huntington Disease (Huntington's Disease) 10/2017
1	Dyslipidemias (Dyslipidemia) 04/2014
1	Atherosclerosis 03/2014
1	Stable Angina 07/2013
1	Diabetes Mellitus 07/2013
1	Multiple Sclerosis 01/2013
1	Ischemia 05/2012
1	Brain Ischemia (Cerebral Ischemia) 05/2012
1	Carcinoma (Carcinomatosis) 01/2012
1	Memory Disorders (Memory Loss) 03/2011
1	Congenital Abnormalities (Deformity) 07/2009
1	Inborn Genetic Diseases (Disease, Hereditary) 07/2009

Drug/Important Bio-Agent (IBA)

33	Proteins (Proteins, Gene)FDA Link 11/2021 - 01/2009
11	biliverdin reductaseIBA 04/2019 - 01/2011
10	Insulin (Novolin)FDA Link 11/2021 - 09/2014
7	Glucose (Dextrose)FDA LinkGeneric 04/2021 - 01/2011
7	ProteomeIBA 01/2021 - 02/2009
6	Pharmaceutical PreparationsIBA 01/2021 - 12/2010
6	Biomarkers (Surrogate Marker)IBA 12/2018 - 04/2011
5	AntioxidantsIBA 01/2022 - 01/2011
5	Amyloid (Amyloid Fibrils)IBA 12/2018 - 09/2014
4	Peptides (Polypeptides)IBA 04/2019 - 09/2014
4	Free RadicalsIBA 01/2016 - 10/2014
4	Atorvastatin (Lipitor)FDA Link 07/2013 - 03/2011
3	HexosaminesIBA 04/2021 - 10/2018
3	tau Proteins (tau Protein)IBA 12/2018 - 01/2018
3	Advanced Glycation End ProductsIBA 05/2015 - 07/2013
3	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 02/2014 - 01/2011
3	Heme Oxygenase-1IBA 07/2013 - 01/2012
2	Protein AggregatesIBA 11/2021 - 08/2013
2	Phosphotransferases (Kinase)IBA 01/2021 - 06/2015
2	Insulin ReceptorIBA 01/2020 - 01/2019
2	Sirolimus (Rapamycin)FDA Link 01/2019 - 01/2018
2	UbiquitinIBA 10/2018 - 01/2016
2	TOR Serine-Threonine KinasesIBA 10/2017 - 01/2016
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2014 - 07/2013
2	Heme (Haem)IBA 08/2012 - 04/2011
2	Tyrosine (L-Tyrosine)FDA Link 04/2011 - 01/2009
2	Threonine (L-Threonine)FDA Link 04/2011 - 01/2011
2	Serine (L-Serine)FDA Link 04/2011 - 01/2011
2	EnzymesIBA 01/2011 - 01/2009
1	Neuroprotective AgentsIBA 01/2022
1	ManganeseIBA 01/2021
1	Endoplasmic Reticulum Chaperone BiPIBA 06/2020
1	Metformin (Glucophage)FDA LinkGeneric 06/2020
1	CytokinesIBA 10/2017
1	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 10/2017
1	Cathepsin DIBA 12/2016
1	AutoantibodiesIBA 01/2016
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016
1	Insulin Receptor Substrate ProteinsIBA 06/2015
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2014
1	Blood Glucose (Blood Sugar)IBA 09/2014
1	CholesterolIBA 04/2014
1	Blood Proteins (Serum Proteins)IBA 01/2013
1	SerpinsIBA 01/2012
1	AnnexinsIBA 01/2012
1	Cyclophilin AIBA 01/2012
1	Biliverdine (Biliverdin)IBA 04/2011
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2011
1	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2010
1	Wheat Germ AgglutininsIBA 12/2010
1	HSP27 Heat-Shock ProteinsIBA 05/2010
1	ThioredoxinsIBA 05/2010
1	LipidsIBA 06/2009
1	Apoptosis Regulatory ProteinsIBA 04/2009
1	Concanavalin AIBA 02/2009

Therapy/Procedure

2	Activities of Daily Living (ADL) 04/2014 - 03/2011
1	Therapeutics 01/2017
1	Drug-Eluting Stents 07/2013
1	Stents 07/2013
1	Percutaneous Coronary Intervention 07/2013
1	Glycemic Control 07/2013